Nodular Fasciitis in the Cavity of Auricular Concha: A Case Report

xlomafota13 shared this article with you from Inoreader Nodular Fasciitis in the Cavity of Auricular Concha: A Case Report Via ear nose throat Ear Nose Throat J. 2021 Apr 8:1455613211006006. doi: 10.1177/01455613211006006. Online ahead of print. ABSTRACT Nodular fasciitis (NF) has a low incidence, many classification subtypes and large histological variations. We describe a 17-month-old child who presented with a mass in the right cavity of auricular concha that was successfully cured by 2 procedures. In pediatric patients with fibroproliferative lesions, the possibility of NF should be excluded to avoid misdiagnos is and overtreatment. PMID:33829880 | DOI:10.1177/01455613211006006 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Porcine endometrial 3D co-culture: Morphological changes in 3D endometrium tissues according to hormonal changes

xlomafota13 shared this article with you from Inoreader Porcine endometrial 3D co-culture: Morphological changes in 3D endometrium tissues according to hormonal changes Via Cellular and Molecular Biology Histol Histopathol. 2021 Apr 8:18335. doi: 10.14670/HH-18-335. Online ahead of print. ABSTRACT Cells cultured as monolayers proliferate well, but do not sustain their differentiation characteristics. Previous studies have investigated the interactions between cells and growth factors or cytokines by establishing either in vivo or in vitro three-dimensional (3D) cultures. Using porcine uterine epithelial cells and endometrial cells, the current study was designed to develop a 3D uterine culture system and investigate the response to hormone treatment. Formation of the 3D uterine model was similar to that of uterus from the group supplemented with calcium and magnesium, and the addition of these ions altered the spectrum of basement membrane degrading enzyme expression and activity. In particular, the epithelial cell junctions in the 3D model most closely resembled those of an actual uterus when the medium was supplemented with calcium a nd magnesium; the intercellular basement membrane structure was also tall under these conditions. The study confirmed that Casp-3 expression was lowest in the P4 (progesterone) treatment group, and this hormone was the most potent stimulus for formation of the endometrial cell layer. Therefore, the addition of calcium and magnesium plays an important role in the formation of a 3D uterine model, and the addition of P4 hormone mimics uterine thickening by stimulating growth of the epithelial cell layer. PMID:33829420 | DOI:10.14670/HH-18-335 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Digging Into Dermatillomania: Scalp Reconstruction in a Complex Patient

xlomafota13 shared this article with you from Inoreader Digging Into Dermatillomania: Scalp Reconstruction in a Complex Patient Via Eplasty Eplasty. 2021 Mar 27;21:ic3. eCollection 2021. NO ABSTRACT PMID:33828637 | PMC:PMC7997828 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Evaluation of hearing preservation in adults with a slim perimodiolar electrode

xlomafota13 shared this article with you from Inoreader Evaluation of hearing preservation in adults with a slim perimodiolar electrode Via http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino Eur Arch Otorhinolaryngol. 2021 Apr 8. doi: 10.1007/s00405-021-06755-z. Online ahead of print. ABSTRACT PURPOSE: Numerous endeavors have been undertaken to preserve hearing in cochlear implant (CI) patients. Particularly, optimization of electrode array design aims at preservation of residual hearing (RH). This study examines whether a slim perimodiolar (PM) electrode array could bear the capability to preserve hearing. METHODS: A total of 47 patients underwent cochlear implantation receiving the PM electrode. (i) Patients with pure tone audiogram (PTA) thresholds better than 85 dB and/or hearing loss for Freiburg speech test numbers less than 60 dB and more than 50% maximum monosyllabic understanding were assigned to the RH group (n = 17), while all others belonged to the noRH group (n = 30). (ii) Another group implanted with a slim straight, lateral wall (LW) electrode was recruited for comparison. RESULTS: We compared 17 RH-30 noRH patients all receiving the PM electrode. RH in PM recipients decreased faster than in LW recipients. No significant differences were observed between both (RH v/s noRH) groups in NRT thresholds, Freiburg speech test and A§E® phonemes. Analogous satisfaction levels were indicated through the questionnaires in terms of sound quality, hearing in silence, noise and directional hearing in both groups. CONCLUSIONS: The results suggest that hearing preservation is influenced not only by electrode shape but various factors. This study opens an avenue for further investigations to elucidate and enumerate the causes for progressive hearing loss. PMID:33830367 | DOI:10.1007/s00405-021-06755-z View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

The occult foreign body in the larynx

xlomafota13 shared this article with you from Inoreader The occult foreign body in the larynx Via hno HNO. 2021 Apr 8. doi: 10.1007/s00106-021-01043-y. Online ahead of print. NO ABSTRACT PMID:33830301 | DOI:10.1007/s00106-021-01043-y View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Endoscopic Left Central Lymph Node Dissection of Thyroid Cancer: Safe, Feasible, and Relatively Easy

xlomafota13 shared this article with you from Inoreader Endoscopic Left Central Lymph Node Dissection of Thyroid Cancer: Safe, Feasible, and Relatively Easy Via radioactive iodine Surg Innov. 2021 Apr 8:1553350620983640. doi: 10.1177/1553350620983640. Online ahead of print. ABSTRACT Purpose. The purpose of this study was to explore the feasibility of left central lymph node dissection (CLND) in endoscopic thyroidectomy via chest-breast approach (ETCB). Methods. Retrospective analysis of 57 cases of left CLND (group A) via ETCB, 35 cases of open left CLND (group B), and 90 cases of right CLND via ETCB (Group C) were performed from October 2014 t o October 2019. Surgical data, complications, and follow-up data were compared among group A and group B, group A and group C, respectively. Results. There were no significant differences between group A and group B in intraoperative blood loss, tumor size, lymph node (LN) metastasis rate, dissected LN number, metastatic LN number, serum thyroglobulin (sTg), radioactive iodine uptake (RAIU), radioactive technetium uptake (RATU), radionuclide imaging of the residual area (RITRA), and radionuclide imaging of suspicious lymph node metastasis (RISLNM). There were no significant differences between group A and group C in age, operation time, intraoperative blood loss, postoperative hospital stay, tumor size, LN metastasis rate, dissected LN number, metastatic LN number, hypoparathyroidism, sTg, RAIU, RATU, RITRA, and RISLNM. There were 5 cases of temporary recurrent laryngeal nerve (RLN) palsy and 1 case of recurrence in group C. Besides, 1 case of lymphatic leakage was in group A . Conclusion. For selected cases, endoscopic left CLND is safe, feasible, efficient, and more easier than endoscopic right CLND. PMID:33830818 | DOI:10.1177/1553350620983640 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Microbiome profiling of uncinate tissue and nasal polyps in patients with chronic rhinosinusitis using swab and tissue biopsy

xlomafota13 shared this article with you from Inoreader Microbiome profiling of uncinate tissue and nasal polyps in patients with chronic rhinosinusitis using swab and tissue biopsy Via Nasal diseases by Sung-Woo Cho, Dong-Young Kim, Sungmi Choi, Sungho Won, Hye-Ryun Kang, Hana Yi Chronic rhinosinusitis (CRS) is characterized according to the presence or absence of nasal polyps (NPs) and displays nasal microbiota dysbiosis. However, optimal sampling methods of the nasal microbiome in CRS have not been identified. We aimed to assess the microbial composition in patients with CRS, comparing different sampling methods (swab and tissue biopsy), tissue types (uncinate tissue and NP), and disease subtypes. Samples were obtained by swabbing the middle meatus and taking a biopsy of uncinate tissue (UT) in patients with CRS with (CRSwNP, N = 8) or without NP (CRSsNP, N = 6) and controls (N = 8). NPs were also harvested in CRSwNP. DNAs were extracted from fifty-two samples and analyzed by 16S rRNA gene amplicon sequencing. As a result, a great interpersonal variance was observed in nasal swabs, while UT samples presented distinct microbiome with low inter-personal differences. Moreover, the UT microbiomes were further differentiated into three clusters which are associa ted with disease status (control, CRSsNP, and CRSwNP). Compared to UT, NP revealed a unique microbiome profile with significantly less bacterial diversity. Prevotella was the genus whose abundance was negatively correlated with disease severity in NP. In conclusion, tissue samples are better specimens than nasal swabs for assessing the microbiomes of CRS patients. Several bacteria in UT and NP tissues revealed an association with clinical severity of CRSwNP. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.