Intravascular Guidewire Residue After Endovascular Embolization for Intractable Epistaxis: A Case Report

xlomafota13 shared this article with you from Inoreader Intravascular Guidewire Residue After Endovascular Embolization for Intractable Epistaxis: A Case Report Via ear nose throat Ear Nose Throat J. 2021 Aug 24:1455613211040581. doi: 10.1177/01455613211040581. Online ahead of print. ABSTRACT Endovascular embolization (EE) has become an effective method for the treatment of intractable epistaxis (IE). However, complications such as facial pain, headaches, aphasia, hemiplegia, and transient blindness can also occur during or after surgery. In this article, we report a rare case of IE with residual intravascular guidewire after EE. Open surgery was used t o remove the guidewire. However, to avoid serious complications such as massive hemorrhage, only part of the guidewire was removed. PMID:34427152 | DOI:10.1177/01455613211040581 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Clinical Trial to Reconfirm the Efficacy and Safety of Cefetamet Pivoxil Treatment in Sinusitis Patients: A Double-Blind, Randomized, Parallel Designed, Multicenter, Active Comparator Study (CASIS Study)

xlomafota13 shared this article with you from Inoreader Clinical Trial to Reconfirm the Efficacy and Safety of Cefetamet Pivoxil Treatment in Sinusitis Patients: A Double-Blind, Randomized, Parallel Designed, Multicenter, Active Comparator Study (CASIS Study) Via ear nose throat Ear Nose Throat J. 2021 Aug 24:1455613211036236. doi: 10.1177/01455613211036236. Online ahead of print. ABSTRACT OBJECTIVE: To evaluate the clinical efficacy and safety of cefetamet pivoxil for the treatment of acute bacterial rhinosinusitis in Korean patients compared to treatment with cefdinir. METHODS: A prospective, multicenter, randomized double-blind, comparative study was conducted by the Departments of Otorhinolaryngology-Head and Neck Surgery at 17 hospitals o r universities in the Republic of Korea from March 2017 to April 2019. A total of 309 patients were screened and 249 patients participated in the study. RESULTS: Treatment with cefetamet pivoxil for 2 weeks showed 82.4% clinical cure and improvement rates in patients with acute bacterial rhinosinusitis compared to 84.68% in those taking cefdinir for 2 weeks, showing that cefetamet pivoxil administered twice a day for 2 weeks was as effective as cefdinir 3 times a day for 2 weeks for the treatment of acute bacterial rhinosinusitis. The overall adverse reaction rates of both drugs were 10.56% in the cefetamet pivoxil group and 15.49% in the cefdinir group, without serious adverse events or drug reactions. CONCLUSIONS: Cefetamet pivoxil twice a day was as efficacious and safe as cefdinir 3 times a day for the treatment of acute bacterial rhinosinusitis, which suggested that cefetamet pivoxil may be a suitable alternative to cefdinir. PMID:34427151 | DOI:10.1177/01455613211036236 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Subjective Voice Outcomes in Surgeon Versus Technician-Monitored Recurrent Laryngeal Nerves in Thyroidectomy

xlomafota13 shared this article with you from Inoreader Subjective Voice Outcomes in Surgeon Versus Technician-Monitored Recurrent Laryngeal Nerves in Thyroidectomy Via ear nose throat Ear Nose Throat J. 2021 Aug 24:1455613211037635. doi: 10.1177/01455613211037635. Online ahead of print. ABSTRACT OBJECTIVES: To compare subjective voice outcomes and postoperative laryngoscopic examination findings of patients with subjective voice complaints between surgeon-monitored and certified technician-monitored thyroidectomies. METHODS: Patients who underwent hemithyroidectomy, total thyroidectomy, and completion thyroidectomy using a nerve monitoring system be tween November 2015 and June 2018 were included in the study. Retrospective chart review was carried out to assess how often patients reported voice changes and to record postoperative flexible laryngoscopic findings of patients when that examination was performed. Data were analyzed using the χ2 test to identify significant differences in outcomes for the 2 groups. RESULTS: A total of 293 procedures was performed among 3 surgeons. Surgeons monitored the nerves in 147 cases and a certified technician monitored the nerves in 146 cases. Subjective voice changes were identified in 11 (7.48%) cases in the surgeon-monitored group and in 20 (13.70%) cases in the technician-monitored group (P = .084). Among the patients who expressed subjective voice changes, 7 patients were identified with vocal cord hypomobility or immobility in the surgeon-monitored group and 13 patients had an abnormal examination in the technician-monitored group (P = .234). CONCL USIONS: Subjective voice changes or proven vocal cord mobility problems were not different between surgeon-monitored patients and technician-monitored patients in thyroidectomies. PMID:34427116 | DOI:10.1177/01455613211037635 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Effects of Gynostemma pentaphyllum on spinal cord motor neurons and microglial cells in vitro

xlomafota13 shared this article with you from Inoreader Effects of Gynostemma pentaphyllum on spinal cord motor neurons and microglial cells in vitro Via histochem Acta Histochem. 2021 Aug 20;123(6):151759. doi: 10.1016/j.acthis.2021.151759. Online ahead of print. ABSTRACT The regenerative capability of spinal cord neurons is limited to impossible. Thus, experimental approaches supporting reconstruction/regeneration are in process. This study focused on the evaluation of the protective potency of an extract from Gynostemma pentaphyllum (GP), a plant used in traditional medicine with anti-oxidative and neuroprotective activities, in vit ro on organotypic spinal cord cultures, the motor-neuron-like NSC-34 cell line and the microglial cell line BV-2. Organotypic cultures were mechanically stressed by the slicing procedure and the effect of GP on motor neuron survival and neurite sprouting was tested by immunohistochemistry. NSC-34 cells were neuronal differentiated by using special medium. Afterwards, cell survival (propidium iodide/fluorescein diacetate labeling), proliferation (BrdU-incorporation), and neurite sprouting were evaluated. BV-2 cells were stimulated with LPS/interferon γ and subjected to migration assay and nanoparticle uptake. Cell survival, proliferation and the expression pattern of different microglial activation markers (cFOS, iNOS) as well as transcription factors (PPARγ, YB1) were analyzed. In organotypic cultures, high-dose GP supported survival of motor neurons and especially of the neuronal fiber network. Despite reduced neurodegeneration, however, there was a GP-mediated activation of astr o- and microglia. In NSC-34 cells, high-dosed GP had degenerative and anti-proliferative effects, but only in normal medium. Moreover, GP supported the neuro-differentiation ability. In BV-2 cells, high-dosed GP was toxic. In lower dosages, GP affected cell survival and proliferation when combined with LPS/interferon γ. Nanoparticle uptake, migration ability, and the transcription factor PPARγ, however, GP affected directly. The data suggest positive effects of GP on injured spinal motor neurons. Moreover, GP activated microglial cells. The dual role of microglia (protective/detrimental) in neurodegenerative processes required further experiments to enhance the knowledge about GP effects. Therefore, a possible clinical use of GP in spinal cord injuries is still a long way off. PMID:34425524 | DOI:10.1016/j.acthis.2021.151759 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Reliability and Correlations Between Overall Severity, Roughness and Breathiness in the Perception of Dysphonic Voices: Investigating Cognitive Aspects

xlomafota13 shared this article with you from Inoreader Reliability and Correlations Between Overall Severity, Roughness and Breathiness in the Perception of Dysphonic Voices: Investigating Cognitive Aspects Via Journal of Voice this study concerns the subjective perception of the quality of the voice, more particularly in the case of dysphonia. Our general objective is to study the perceptual mechanisms, which constitute Hirano's GRBAS multidimensional perceptual rating scale. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

92. Jahresversammlung der DGHNO-KHT 2021 erstmals im Online-Format – eine kritische Bewertung auf Basis der Teilnehmerevaluation

xlomafota13 shared this article with you from Inoreader 92. Jahresversammlung der DGHNO-KHT 2021 erstmals im Online-Format – eine kritische Bewertung auf Basis der Teilnehmerevaluation Via Laryngo-Rhino-Otologie Laryngorhinootologie DOI: 10.1055/a-1579-8096 Die 92. Jahresversammlung der DGHNO-KHC wurde im Mai 2021 erstmals aufgrund der Corona-bedingten neuen Rahmenbedingungen komplett in einem Online-Format durchgeführt. Den Teilnehmern aus den Reihen der Mitglieder, Gäste und Industriepartner wurde im Anschluss ein Evaluationsfragebogen der zuständigen Landesärztekammer Nordrhein zugesandt, der inhaltlich um Fragen zu dem neuen virtuellen Format ergänzt wurde. Die Publikation fasst die Auswertung der 187 ärztlichen Rückläufer (10 % der Gesamtteilnehmerzahl) und der 25 Industrieaussteller (60 % der Industrieaussteller) zusammen und stellt ein erstes Fazit auf. In der groben Betrachtung wurde der Kongress von den ärzt lichen und wissenschaftlichen Teilnehmern trotz komplett fehlender sozialer und sehr eingeschränkter fachlicher Interaktion überwiegend positiv bewertet. Auf Seiten der Industrie bot sich ein gegenteiliges Bild. Auf die Frage an die ärztlich/wissenschaftlichen Teilnehmenden nach dem zukünftigen Format der nächsten HNO-Jahreskongresse sprachen sich 16 % für einen reinen Online-Kongress, 67 % für einen Präsenzkongress mit Online-Elementen und lediglich 17 % für einen reinen Präsenzkongress aus. Auf die Frage an die Industrie, welche Art der Ausstellung in Zukunft bevorzugt würde, sprachen sich 68 % für die reine Präsenzausstellung im Rahmen eines Präsenzkongresses aus. 32 % konnten sich für Präsenz mit Online-Elementen erwärmen. Eine zukünftig komplette Online-Industrieausstellung wurde mit 0 % Zustimmung abgewählt. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, Germany Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Abdomen and thorax clinical anatomy: from viscera morphology and vascularization to epidural and caudal anesthetic techniques

xlomafota13 shared this article with you from Inoreader Abdomen and thorax clinical anatomy: from viscera morphology and vascularization to epidural and caudal anesthetic techniques Via radiol anat Surg Radiol Anat. 2021 Aug 24. doi: 10.1007/s00276-021-02823-5. Online ahead of print. NO ABSTRACT PMID:34427734 | DOI:10.1007/s00276-021-02823-5 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.