Dutch scoop top ECR prize for breast MRI work

A new method may help improve delineation between malignant and benign breast...

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Breast MRI survey reveals wide variations across Europe

Short is just as sweet for breast MRI protocol

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MRI spots HIV in the brain

Researchers at the University College London have developed a way to use MRI...

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Roles of Dietary Amino Acids and Their Metabolites in Pathogenesis of Inflammatory Bowel Disease

Inflammatory Bowel Disease (IBD) is a kind of chronic inflammation, which has increasing incidence and prevalence in recent years. IBD mainly divides into Crohn’s disease (CD) and ulcerative colitis (UC). It is hard to cure IBD completely, and novel therapies are urgently needed. Amino acids (AAs) and their metabolites are regarded as important nutrients for humans and animals and also play an important role in IBD amelioration. In the present study, the potential protective effects of AAs and their metabolites on IBD had been summarized with the objective to provide insights into IBD moderating using dietary AAs and their metabolites as a potential adjuvant therapy.

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Nuclear Imaging to Detect Diaphragmatic Perforation as a Rare Complication of Microwave Ablation

Acquired diaphragmatic perforation leading to massive hepatic hydrothorax and respiratory failure is a rare complication of microwave ablation (MWA) of hepatocellular carcinoma (HCC). Imaging modalities to detect pleuroperitoneal communication remain poorly described. We report a nuclear imaging technique used to efficiently diagnose and locate diaphragmatic defects. A 57-year-old male with cirrhosis and HCC presented with respiratory distress after undergoing MWA of a HCC lesion. He was admitted to the intensive care unit for noninvasive positive pressure ventilator support. Chest radiography revealed a new large right pleural effusion. Large-volume thoracentesis was consistent with hepatic hydrothorax. The fluid reaccumulated within 24 hours; therefore an acquired diaphragmatic perforation induced by the ablation procedure was suspected. To investigate, Technetium-labeled albumin was injected into the peritoneal cavity. The tracer accumulated in the right hemi thorax almost immediately. The patient then underwent transjugular intrahepatic portosystemic shunting in efforts to relieve portal hypertension and decrease ascites volume. Unfortunately, the patient deteriorated and expired after few days. Although diaphragmatic defects develop in cirrhotic patients, such small fenestrations do not normally lead to rapid development of life-threatening pleural effusion. MWA procedures can cause large diaphragmatic defects. Immediate detection of this complication is essential for initiating early intervention.

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Determinants of Rural Out-Migration in Habru District of Northeast Ethiopia

Migration has become a cause of concern at the global, regional, and national levels. Like the case of many developing countries, Ethiopia has been facing increasing challenges related to rural out-migration. This study aimed to analyze factors that determine rural communities’ decision to migrate to internal and international destinations in Habru district of Northeast Ethiopia. Stratified sampling technique has been employed to select a total of 200 household heads in three agroecologies of the study area. Structured questionnaires have been used as a principal primary data collection method and logistic regression has been employed for analysis. The results of the study showed that intravillage conflict, absence of relief assistant, livestock ownership, farm land size, access to information, and household and individual characteristics including family size, sex, and age of the migrants are the dominant determinant factors for rural out-migration. Migration can have a positive outcome in improving livelihoods if comprehensive and holistic policies and strategies are in place. There is also a need to strengthen the link between rural development policy and the disadvantaged groups by designing and implementing different livelihood alternatives including reducing pressure on scarce resources particularly land, integrating health and education services, and creating nonfarm employment opportunities.

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Epidemiological Characteristics of Dengue Disease in Latin America and in the Caribbean: A Systematic Review of the Literature

Dengue, an important mosquito-borne virus transmitted mainly by Aedes aegypti, is a major public health issue in Latin America and the Caribbean. National epidemiological surveillance systems, usually based on passive detection of symptomatic cases, while underestimating the true burden of dengue disease, can provide valuable insight into disease trends and excess reporting and potential outbreaks. We carried out a systematic review of the literature to characterize the recent epidemiology of dengue disease in Latin America and the English-speaking and Hispanic Caribbean Islands. We identified 530 articles, 60 of which met criteria for inclusion. In general, dengue seropositivity across the region was high and increased with age. All four virus serotypes were reported to circulate in the region. These observations varied considerably between and within countries and over time, potentially due to climatic factors (temperature, rainfall, and relative humidity) and their effect on mosquito densities and differences in socioeconomic factors. This review provides important insight into the major epidemiological characteristics of dengue in distinct regions of Latin America and the Caribbean, allowing gaps in current knowledge and future research needs to be identified.

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Failure of fertility therapy is associated with increased risk of cardiovascular events

Women who undergo fertility therapy but do not give birth have a higher risk of long term adverse cardiovascular events than those who undergo therapy and do give birth, a population based,...

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