Association between pain severity and clinico-histopathological findings in the mandibular canal and inferior alveolar nerve of patients with advanced mandibular osteoradionecrosis

Pain is one of the most problematic symptoms in patients with osteoradionecrosis (ORN) of the jaws. This study investigated the associations between pain severity and morphological alterations of the mandibular canal (MC) and inferior alveolar nerve (IAN), in respective computerized tomography (CT) images and resected specimens of mandibular ORN.

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