Sputum transcriptomics reveal up-regulation of IL-1 receptor family members in severe asthma

The study shows the value of sputum transcriptomics for understanding severe asthma mechanisms and identifies different IL-1R family members with different inflammatory phenotypes. Suppressing the inflammasome attenuates Th2 and non-Th2 features in vivo.

from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2rt4VfF
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