Dear Editor, Extensive skin defects can be a challenging problem for a reconstructive surgeon. Primary closure of such defects is limited by tension and ischemia that develop at the skin edges. In such situation, skin grafting, locoregional, or free flap surgery are often necessary. We want to share our experience in achieving primary closure of extensive wounds with the TopClosure system (IVT Medical Limited, Israel) in combination with negative pressure therapy. The external tissue expansion effect of the TopClosure and the wound contracting ability of negative pressure therapy synergistically facilitates primary closure of extensive defects.
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