Endothelial Wnt/{beta}-catenin signaling reduces immune cell infiltration in multiple sclerosis [Immunology and Inflammation]

Disruption of the blood–brain barrier (BBB) is a defining and early feature of multiple sclerosis (MS) that directly damages the central nervous system (CNS), promotes immune cell infiltration, and influences clinical outcomes. There is an urgent need for new therapies to protect and restore BBB function, either by strengthening endothelial...

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