Role of C/EBP homologous protein (CHOP) and Endoplasmic Reticulum in Asthma Exacerbation by Regulating the IL-4/STAT6/Tfec/IL-4Rα Positive Feedback Loop in M2 Macrophages

CHOP exacerbates allergic asthma by regulating the IL-4/STAT6/Tfec/IL-4Rα positive feedback loop essential for M2 programming in macrophages, which are positively correlated with disease severity in asthmatic patients.

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