Elucidation of roles for vitamin B12 in regulation of folate, ubiquinone, and methionine metabolism [Microbiology]

Only a small fraction of vitamin B12-requiring organisms are able to synthesize B12 de novo, making it a common commodity in microbial communities. Initially recognized as an enzyme cofactor of a few enzymes, recent studies have revealed additional B12-binding enzymes and regulatory roles for B12. Here we report the development...

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