Necroptosis is a physiological cell suicide mechanism initiated by receptor-interacting protein kinase-3 (RIPK3) phosphorylation of mixed-lineage kinase domain-like protein (MLKL), which results in disruption of the plasma membrane. Necroptotic cell lysis, and resultant release of proinflammatory mediators, is thought to cause inflammation in necroptotic disease models. However, we previously showed...
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Abstract Blinatumomab is a bispecific T-cell engaging αCD19 antibody used in refractory or relapsed B-cell precursor acute lymphoblastic l...
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Exposure to asbestos is the main cause of malignant pleural mesothelioma (MPM), a highly aggressive cancer of the pleura. Since the only too...
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About 540 million years ago a group of jellyfish washed ashore, died and fossilised – preserving evidence of the earliest example of an anim...
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5 Essential Oils for Relieving Your Allergy Symptoms Reader's Digest The minty scent can also unstuff your sinuses and may even ...
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The pursuit for clarity in diagnostic and treatment pathways for the complex, chronic condition of myalgic encephalomyelitis/chronic fatigue...
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Publication date: Available online 11 November 2017 Source: Clinical Biochemistry Author(s): Chao-Hui Dong, Zhang-Min Wang, Si-Yu Chen Ob...
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by Tiancheng Zhao, Changfeng Li, Yanhua Wu, Bingjin Li, Bin Zhang Programmed death-ligand 1 (PD-L1) is a promising target of cancer immune ...
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Transit accessibility is an important measure on the service performance of transit systems. To assess whether the public transit service is...
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Obesity is a major risk factor in the development of conditions such as hypertension, hyperglycemia, dyslipidemia, coronary artery disease, ...
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