Appraise the Health-Related Quality of Life among Trauma Patients

2016-12-01T16-50-10Z
Source: International Journal of Health and Rehabilitation Sciences (IJHRS)
Ravi Kant Jain, Neelesh Dhadse, Chirag Sethi, Ravindra Kumar, Susmit Kosta.
Background: Limb injures is revolve a life-changing event that can cause significant disruptions in many important areas of life. Objectives: The objective of our study was to appraise the Health Related Quality of Life (HRQOL) and psychosocial factors associated with pain and disability in patients following Upper limb (UL) and lower limb (LL) trauma patients Materials and methods: A sample of convenience 300 adult male and female patients who met the inclusion criteria was included. A short form (36) health status questionnaire was filled by a single author from each patient after one year of follow up. This part was utilized to assess the QOL among limbs traumas patients. Results: Intraclass correlation coefficients were greater than 0.7 in five of the eight domains of SF 36 except mental health, social function and general health. Chronbachs α was higher than 0.8 all the domains except in social function domain. There was no difference in Health Related Quality of Life in patients with upper and lower limb trauma. However there was significant difference in 4 domains related to physical components of SF 36 survey form between male and females. Conclusion: Both upper and lower limb trauma similarly affects the Health Related Quality of Life in all age group of patients. Keywords: Sf-36, Trauma, HRQOL


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Levels of toxic metals and trace elements in autopsy liver tissue samples

2016-12-01T07-22-30Z
Source: Medicine Science | International Medical Journal
Servet Birgin Iritas, Ahmet Hakan Dinc, Aybike Dip, Bahri Melih Unal, Mevlut Ertan, Tulin Soylemezoglu.
The aim of the study is to determine the levels of toxic metals (cadmium and lead) and trace elements (zinc and copper) in the liver tissues of autopsy cases in Ankara and to evaluate the statistical relationship of these metals with subjects physical properties, smoking status, occupational exposure and environmental factors. Results are expected to establish the average burden of involved metals in liver tissue of Turkish population. Hepatic trace elements and toxic metal levels were assessed in 119 autopsy cases. Digestion procedure for liver tissues was carried out using a Mars Xpress microwave system (CEM, Matthews, USA) with PTFE microwave digestion vessels. Lead and cadmium were analyzed by Graphite Furnace Atomic Spectrometry; copper and zinc were analyzed by Flame Atomic Absorption Spectrometry. Average liver levels of metals and trace elements were found 29.5 µg/g, 216 µg/g, 0.39 µg/g and 4.38 µg/g dry weight for copper, zinc, lead and cadmium, respectively. Copper and lead levels were found higher in men. There was a significant decrease in copper levels with age. Lead levels in city dwellers were significantly higher and there was no correlation between metal levels and occupations of the individuals. Significant increase in copper, lead and cadmium were observed in smokers liver tissues. All metal levels were compared with each other and positive correlation was found between zinc-copper, lead-zinc and copper-zinc levels (p˂0.01). In Turkey, it is the first study which gives liver tissue levels of trace elements and heavy metals of autopsy samples in a city which has a median-scale industrial development.


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Severe major depression: a case of neurobrucellosis

2016-12-01T07-22-30Z
Source: Medicine Science | International Medical Journal
Lara Utku Ince, Nursel Akti Kavuran, Abdulcemal Ozcan, Suheyla Unal.



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Langerhans Cell Histiocytosis In Postauricular Region

2016-12-01T06-58-27Z
Source: The Southeast Asian Journal of Case Report and Review
Karthikeyan Ramasamy, John Kiran Rayer, Sivaraman Ganesan, Arun Alexander, Sunil Kumar Saxena.
We present a rare case report of eosinophilic granuloma in 10 year old female which was managed surgically. We also review the case literature, the clinical presentations briefly with surgical management.


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Unique Pearls In Synergy-Atrial Myxoma And Hypertrophic Cardiomyopathy

2016-12-01T06-58-27Z
Source: The Southeast Asian Journal of Case Report and Review
Avinash Mani, Manoj Kumar, Vineeta Ojha.
Primary cardiac tumors are a rare occurrence amongst general population, myxoma being the most common benign primary cardiac tumor. Hypertrophic cardiomyopathy(HCM) is a genetic cardiovascular disorder which usually presents with syncope or palpitations. The case we present here is a unique amalgamation of both these pathologies which are uncommon as well as completely unrelated to each other as far as literature describes. The patient presented with symptoms of congestive cardiac failure without any history of syncope and palpitation ,however echocardiography revealed the presence of HCM as well as atrial myxoma. This case reveals that remote possibility of such coexisting conditions should be kept in mind in clinical practice and also the fact that HCM can notoriously remain undetected presenting only as heart failure instead of its usual clinical features.


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Maternal And Perinatal Outcome In Antepartum Hemorrhage :At Sir T Hospital

2016-12-01T06-58-27Z
Source: The Southeast Asian Journal of Case Report and Review
Mehul Patel, Kanaklatta Nakum, Mayank Lunagariya, Juhi Patel.
Introduction: Antepartum haemorrhage is one of the major causes of maternal mortality. It contributes to 15-20% of maternal mortality in India. Incidence of antepartum haemorrhage is varies from 2-5 % of all deliveries. APH arising from placental abruption and placenta praevia is associated with an increased risk of postpartum haemorrhage 1 .Maternal and perinatal complication of antepartum haemorrhage are anaemia, postpartum haemorrhage, shock, low birth weight, intrauterine death, and birth asphyxia. Aim & Objectives: 1) To study Maternal and Perinatal outcome in Antepartum haemorrhage. 2) to study factors associated with Antepartum haemorrhage. Method & Materials: It is retrospective study carried out on 56 women admitted with the diagnosis of antepartum haemorrhage at Sir T. Hospital Bhavnagar during August 2015 to July 2016. The diagnosis was made on the basis of history, Clinical examination and few cases aided by ultrasonography. Result: In present study the incidence of APH was 1.4%. out of 56 cases 66% were multigravida and 71% of them were of low socio economic status.56% had feature of pre-eclampsia. Maternal and perinatal mortality was very high with increase rates of anaemia (100%), caesarean section rate (61%), need of blood transfusion (86%), coagulation failure (13%), low birth weight (75%). Perinatal mortality was 43%.


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Retinopathy of prematurity: incidence and risk factors: a hospital based study from Shimla, Himachal Pradesh, India

2016-12-01T03-48-47Z
Source: International Journal of Research in Medical Sciences
Nitin Kumar, Shayam L. Kaushik, Neelam Grover, Ram L. Sharma.
Background: The blindness due to retinopathy of prematurity (ROP) is avoidable, if it is detected in time by screening. With increasing survival of preterm and low birth weight newborns in neonatal units, who are on prolonged oxygen therapy and mechanical ventilation; ROP is bound to affect these babies. This study was planned to investigate the incidence and the risk factors of ROP in a tertiary care institute in Himalayan region of north India. Methods: This was a hospital based prospective study, conducted at neonatal intensive care units at IGMC, Shimla, from June 2011 to July 2012. 64 premature and low birth weight neonates born or admitted for neonatal intensive care unit (NICU) were screened for ROP using indirect ophthalmoscope. Cases found positive for ROP were closely followed up and managed as per international guidelines. Results: Out of 64 neonates, 14 were lost to follow up and 50 babies were enrolled in the study. Out of them 21 were males and 29 were females. Among them 3 male and 5 female newborns developed ROP. Mean gestational age of babies with ROP was 30.63 weeks. ROP was significantly associated with oxygen administration (p=0.027), RDS (p=0.003), septicaemia (p=0.028) and exchange transfusion (p=0.003). Apneic spells, surfactant administration, hyperbilirubinemia, phototherapy, blood transfusion and maternal factors were not associated with increased risk of ROP. Conclusions: For premature infants with birth weight less than 1200 grams, who has received prolonged oxygen therapy, associated respiratory distress and had received exchange transfusion the screening of ROP should be done at most appropriate time that is 32 - 40 weeks of gestational age. Timely referral of detected ROP cases for early treatment prevents blindness. There is a need for the obstetricians, neonatologist and ophthalmologist to work in close co-operation to prevent blindness due to ROP.


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